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Lurasidone Hydrochloride

Published: July 26, 2026Updated: August 28, 2026

Lurasidone Hydrochloride is an atypical antipsychotic medication used to treat schizophrenia and bipolar depression in adults and certain pediatric patients. It works by blocking dopamine and serotonin receptors in the brain to help reduce psychotic symptoms and improve mood.

Quick summary

A prescription antipsychotic for schizophrenia and bipolar depression that works by blocking dopamine and serotonin receptors.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1040027
Generic
Lurasidone Hydrochloride
Class
pin-variant
Brands
Latuda
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Schizophrenia in adults and adolescents (ages 13-17); bipolar depression associated with bipolar I disorder in adults and pediatric patients (ages 10-17). It is not typically used for bipolar mania.

Lurasidone is a second-generation atypical antipsychotic that primarily blocks dopamine D2 receptors and serotonin 5-HT2A receptors in the brain, helping to reduce psychotic symptoms and alleviate depressive moods.

Must be taken with food (at least 350 calories) for proper absorption. Common side effects include drowsiness, nausea, restlessness, and movement disorders. May cause weight gain, elevated blood sugar, and increased cholesterol. Not recommended for elderly patients with dementia-related psychosis. Avoid operating machinery until you know how it affects you.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy