Triptorelin
Lutrate is a brand-name formulation of leuprolide acetate, a GnRH agonist medication. It works by initially stimulating, then suppressing the pituitary gland's production of hormones that regulate sex hormones. This medication is primarily used in the treatment of hormone-sensitive cancers and certain gynecological conditions.
Lutrate is a GnRH agonist injection used to treat hormone-responsive cancers and conditions by suppressing sex hormone production.
Key facts at a glance
- RxNorm
- 2709443
- Generic
- Lutrate
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Lutrate is indicated for the treatment of advanced prostate cancer, breast cancer, endometriosis, and uterine fibroids. It may also be used for central precocious puberty and anemia caused by uterine fibroids.
As a GnRH agonist, Lutrate initially stimulates the pituitary gland to increase hormone release, but with continued administration, it causes desensitization of the pituitary, leading to decreased production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This results in reduced production of testosterone and estrogen, depriving hormone-sensitive tissues and tumors of their growth stimulation.
Lutrate is administered as a depot injection, typically monthly or quarterly. Common side effects include hot flashes, injection site reactions, and decreased bone density with long-term use. Patients may experience an initial symptom flare before improvement. It should only be used under the supervision of a healthcare provider experienced in cancer or hormone therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy