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Macrobid

Published: July 26, 2026Updated: August 25, 2026

Macrobid is a brand-name antibiotic containing nitrofurantoin used to treat and prevent urinary tract infections. It works by killing bacteria that cause infections in the urinary system. This medication is primarily prescribed for uncomplicated bladder infections and is not typically used for kidney infections.

Quick summary

Macrobid is an antibiotic used to treat and prevent urinary tract infections by killing bacteria in the urinary tract.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
152001
Generic
Macrobid
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Macrobid is used to treat acute uncomplicated urinary tract infections (UTIs) and prevent recurrent UTIs. It is effective against certain gram-positive and gram-negative bacteria commonly responsible for bladder infections.

Nitrofurantoin, the active ingredient in Macrobid, works by inhibiting bacterial cell wall synthesis and damaging bacterial DNA. This bactericidal action is concentrated in the urine, making it particularly effective for urinary tract infections.

Macrobid should be avoided in patients with severe kidney impairment and is not recommended near term pregnancy or in infants under one month old. Common side effects include nausea, headache, and urine discoloration. Rare but serious side effects may include lung reactions with prolonged use and peripheral neuropathy. Take with food to improve absorption and reduce stomach upset.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy