Macrosyn (Isotretinoin): Patient Guide for Severe Acne
Macrosyn is a brand of isotretinoin, an oral vitamin A derivative used to treat severe acne that has not responded to other treatments. It reduces skin oil production and helps prevent clogged pores and scarring, but it must be used under medical supervision.
Macrosyn can be effective for severe acne, but it may cause serious side effects and severe birth defects. Do not take it without a clinician’s prescription and discuss pregnancy prevention, monitoring, and other medicines with your doctor or pharmacist.
Key facts at a glance
- RxNorm
- 2479131
- Generic
- Macrosyn
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy