Makena (Progesterone Injection): Uses, Side Effects, and How to Take It
Makena is an injectable form of progesterone used to help lower the risk of preterm birth in certain pregnancies. It is prescribed for a singleton pregnancy when the patient has had at least one previous spontaneous preterm birth.
Makena is given as weekly injections during the middle and later parts of pregnancy to help reduce the risk of preterm birth. Use it only as prescribed, and talk with your doctor or pharmacist if you have any concerns.
Key facts at a glance
- RxNorm
- 1087965
- Generic
- Makena
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy