Mandelic Acid
Mandelic acid is an aromatic alpha-hydroxy acid that has been used for urinary acidification and as a component in certain perfusion solutions. It has antimicrobial properties that made it historically useful in treating urinary tract infections, particularly when acidification of urine was desired.
An organic acid used for urinary acidification and historically in urinary tract infection treatment.
Key facts at a glance
- ATC
- B05CA06
- RxNorm
- 29256
- Generic
- Mandelic Acid
- Class
- atc-b05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for urinary acidification and as a urinary antiseptic. May be employed in perfusion solutions. Dermatological formulations exist for skin conditions such as acne and photoaging.
As an alpha-hydroxy acid, it exerts antibacterial effects in the urinary tract and helps acidify urine, creating an unfavorable environment for certain pathogens. In topical formulations, it acts as a chemical exfoliant by breaking down desmosomes between skin cells.
Oral formulations may cause gastrointestinal irritation. Topical use may cause skin irritation, redness, or peeling. Use with caution in patients with renal impairment. Consult current prescribing information for appropriate indications and safety profile.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy