Procarbazine
Matulane (procarbazine) is a chemotherapy medication used to treat certain types of cancer, primarily Hodgkin's lymphoma and other lymphomas. It works as an alkylating agent that interferes with DNA and RNA synthesis in cancer cells, helping to stop their growth and division. This medication is typically used in combination with other chemotherapy drugs as part of a treatment regimen.
Matulane is a chemotherapy drug used to treat Hodgkin's lymphoma and other cancers by inhibiting cancer cell DNA and RNA synthesis.
Key facts at a glance
- RxNorm
- 203801
- Generic
- Matulane
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Matulane is primarily used to treat Hodgkin's lymphoma (often in combination with other chemotherapy agents like MOPP regimen), other lymphomas, brain tumors, and occasionally melanoma or lung cancer.
Matulane is an alkylating agent that works by inhibiting protein, RNA, and DNA synthesis in rapidly dividing cells. It causes DNA strand breaks and interferes with cell division, which is particularly effective against cancer cells that divide rapidly.
Matulane requires careful monitoring and has significant drug interactions - particularly with alcohol, sympathomimetics, and foods high in tyramine (aged cheeses, fermented foods) due to MAO inhibitor activity. Common side effects include bone marrow suppression, nausea, and fatigue. Regular blood tests are needed during treatment. Use effective contraception during and after treatment due to potential reproductive effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy