Atovaquone
Mepron (atovaquone) is an antiprotozoal medication used to treat and prevent Pneumocystis jirovecii pneumonia (PCP) and toxoplasmosis, particularly in patients with compromised immune systems such as those with HIV/AIDS who cannot tolerate first-line treatments. It works by inhibiting mitochondrial electron transport in susceptible parasites, disrupting their energy production.
Mepron is an antiprotozoal drug used to prevent and treat PCP and toxoplasmosis in immunocompromised patients.
Key facts at a glance
- RxNorm
- 114972
- Generic
- Mepron
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of Pneumocystis jirovecii pneumonia (PCP) and treatment of toxoplasmosis, primarily used in immunocompromised patients such as those with HIV/AIDS who are intolerant to standard therapies like trimethoprim-sulfamethoxazole.
Atovaquone inhibits the cytochrome bc1 complex in the mitochondrial electron transport chain of susceptible protozoa, disrupting ATP synthesis and energy production necessary for parasite survival.
Must be taken with food to enhance absorption; common side effects include rash, nausea, diarrhea, and headache; not recommended during pregnancy unless benefits outweigh risks; always complete the full prescribed course.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy