Methoxamine
Methoxamine is a synthetic sympathomimetic amine that acts as a selective alpha-1 adrenergic receptor agonist, causing potent peripheral vasoconstriction. It is primarily used as a vasopressor agent to treat acute hypotension and was historically employed in managing certain cardiac arrhythmias. The drug increases blood pressure through direct stimulation of alpha receptors on blood vessels, leading to increased systemic vascular resistance.
Methoxamine is a vasopressor medication that increases blood pressure through alpha-1 adrenergic receptor stimulation.
Key facts at a glance
- ATC
- C01CA10
- RxNorm
- 6853
- Generic
- Methoxamine
- Class
- atc-c01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Acute hypotension (particularly during anesthesia), orthostatic hypotension, and historically for certain supraventricular tachyarrhythmias when bradycardia is desirable.
Acts as a selective alpha-1 adrenergic receptor agonist, causing direct vasoconstriction of peripheral blood vessels, which increases systemic vascular resistance and blood pressure. May also reduce heart rate through baroreceptor reflex.
Should be used with caution in patients with hypertension, hyperthyroidism, or severe cardiovascular disease. Can cause reflex bradycardia. Administration requires careful hemodynamic monitoring. Availability may be limited in many countries.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy