Methylsulfonylmethane
Methylsulfonylmethane (MSM) is an organic sulfur compound commonly used as a dietary supplement for joint and connective tissue support. It is taken to support overall mobility, reduce exercise-induced muscle damage, and promote skin and nail health.
MSM is an over-the-counter sulfur supplement commonly used for joint support and inflammatory conditions.
Key facts at a glance
- RxNorm
- 23247
- Generic
- Methylsulfonylmethane
- Class
- unclassified
- Brands
- Novipet Joint Support
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, capsule, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Commonly used for osteoarthritis, joint pain, and inflammation. Also taken for muscle recovery after exercise, skin elasticity, and as a general supplement for connective tissue health.
Provides bioavailable sulfur that may support collagen synthesis and connective tissue formation. Exhibits anti-inflammatory properties and may help reduce oxidative stress in tissues.
Available over-the-counter as a dietary supplement, not an FDA-approved drug. Generally well-tolerated but may cause mild GI upset in some users. Consult a healthcare provider before use, especially if pregnant, nursing, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 31, 2026. · Read our editorial policy