Mifepristone
Mifeprex (mifepristone) is a prescription medication used to end early pregnancy. It works by blocking the hormone progesterone, which is necessary to maintain pregnancy, causing the lining of the uterus to break down.
Mifeprex is used for medical termination of early pregnancy in combination with another medication.
Key facts at a glance
- RxNorm
- 284781
- Generic
- Mifeprex
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Medical termination of early intrauterine pregnancy (up to 49 days gestation) in combination with misoprostol, as an alternative to surgical procedures.
Mifepeplex is a synthetic steroid that acts as a progesterone receptor antagonist. By blocking progesterone receptors in the uterus, it causes decidual necrosis, cervical softening, and increased uterine sensitivity to prostaglandins, leading to pregnancy termination.
Must be prescribed by or under the supervision of a qualified healthcare provider. Follow-up visit is required to confirm complete termination. Not for use in cases of confirmed or suspected ectopic pregnancy, adrenal failure, or with certain contraindications. FDA-approved with a Risk Evaluation and Mitigation Strategy (REMS) program.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy