Mitomycin
Mitosol (mitomycin) is an alkylating agent used as an adjunct medication in ophthalmic surgery, particularly during glaucoma filtering procedures. It works by inhibiting fibroblast proliferation, which helps prevent excessive scar tissue formation and improves surgical success rates. This medication is administered topically during surgery by trained ophthalmologists.
Mitosol is an ophthalmic antimetabolite used during glaucoma surgery to prevent scar tissue formation.
Key facts at a glance
- RxNorm
- 1244554
- Generic
- Mitosol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used as an adjunct to glaucoma filtering surgery (trabeculectomy) to inhibit wound healing and reduce the risk of surgical failure from scarring. May also be used in other ocular procedures where scar tissue prevention is desired.
As an alkylating agent, it cross-links DNA in rapidly dividing cells, particularly fibroblasts. This inhibits cell division and proliferation, reducing scar tissue formation at the surgical site.
Should only be administered by qualified ophthalmic surgeons. May cause ocular toxicity if improperly applied. Not for intravitreal use. Patients should be monitored for potential complications including hypotony, corneal damage, and endophthalmitis. Contraindicated in patients with hypersensitivity to mitomycin.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy