Mometasone
Mometasone is a topical corticosteroid used to treat inflammatory and itchy skin conditions such as eczema, psoriasis, and allergic reactions. It works by reducing inflammation, relieving itching, and constricting blood vessels in the affected skin areas.
A topical corticosteroid cream or ointment that reduces skin inflammation and itching.
Key facts at a glance
- ATC
- D07AC13
- RxNorm
- 108118
- Generic
- Mometasone
- Class
- atc-d07
- Brands
- Propel, Dulera, Nasonex, Motazol, Mometamax, Sinuva, Posatex, Ryaltris, Simplera, Mometavet, Mometamax Single, Klentz, Asmanex
- Availability
- rx
- Pregnancy
- C
- Lactation
- caution
- Routes
- otic, topical, nasal
- Forms
- inhaler, suspension, solution, ointment, spray, cream
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
10 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits significantly outweigh risks
regular prenatal checkups
Use with caution and monitor for adverse effects.
pregnancy
second third trimesteruse lowest effective dose
use only if clearly needed; avoid high doses or prolonged use
fetal growth monitoring if used long-term
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse lowest effective dose
mometasone may pass into breast milk; use with caution in nursing mothers
monitor infant for signs of corticosteroid exposure
Use with caution and monitor for adverse effects.
pediatric_age
children under 2not recommended
nasal spray formulation not approved for children under 2 years
none applicable
Use of this medication in this population requires careful consideration of risks and benefits.
pediatric_age
children 2 to 11age-appropriate dosing
nasal spray approved for ages 2+; inhaler approved for ages 4+; follow age-specific dosing guidelines
monitor growth with long-term use
geriatric
elderly over 65no specific dose adjustment typically required
use with caution due to increased risk of adverse effects; monitor for systemic corticosteroid effects
periodic assessment of adrenal function and bone density with long-term use
Use with caution and monitor for adverse effects.
renal_impairment
mild to moderateno adjustment typically needed
no specific dose adjustment required for topical or nasal formulations
standard monitoring
renal_impairment
severeno adjustment typically needed
no specific dose adjustment required; monitor for systemic effects
standard clinical monitoring
hepatic_impairment
mild to moderateuse with caution
use with caution; corticosteroids are metabolized in liver
monitor for systemic effects
Use with caution and monitor for adverse effects.
hepatic_impairment
severeuse lowest effective dose
use with caution; increased risk of systemic corticosteroid effects
close monitoring for adrenal suppression
Use with caution and monitor for adverse effects.
Statistics and clinical data
FDA Approval Year
First FDA approval for nasal spray formulation
Drug class
Topical glucocorticoid
Mechanism of action
Anti-inflammatory and immunosuppressive mechanism
Common uses
Therapeutic applications
Treats inflammatory and pruritic skin conditions including atopic dermatitis (eczema), psoriasis, seborrheic dermatitis, and allergic skin reactions.
Exerts anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive effects. The exact mechanism of anti-inflammatory action is not fully understood, but corticosteroids are believed to work by inhibiting inflammatory pathways and reducing immune responses in the skin.
For external use only on the skin. Avoid prolonged or excessive use, especially on large body areas, as systemic absorption may occur. Do not apply to infected, broken, or ulcerated skin unless directed by a physician. Use with caution on the face and in children. Should not be used for extended periods without medical supervision.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy