Hyaluronic Acid
Monovisc is a brand-name hyaluronic acid injection used to treat osteoarthritis of the knee. It is administered directly into the knee joint by a healthcare professional to supplement the natural synovial fluid and provide pain relief. This medication is typically prescribed for patients who have not responded adequately to conservative treatments such as physical therapy and pain relievers.
Monovisc is an injectable hyaluronic acid supplement for knee osteoarthritis pain relief.
Key facts at a glance
- RxNorm
- 1537003
- Generic
- Monovisc
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Monovisc is indicated for the treatment of pain associated with osteoarthritis of the knee in patients who have failed to respond adequately to conservative non-pharmacological therapy and simple analgesics such as acetaminophen.
Monovisc contains high molecular weight hyaluronic acid, which supplements the natural synovial fluid in the knee joint. It acts as a lubricant and shock absorber, helping to restore the viscous properties of the joint fluid and reduce pain by improving joint function.
Monovisc is administered as a single intra-articular injection into the knee. It should only be given by a qualified healthcare professional. Common side effects may include temporary pain, swelling, or stiffness at the injection site. Patients with skin infections or joint infections near the injection site should not receive this treatment. Allergic reactions to hyaluronan products are possible.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy