Moricizine
Moricizine is a Class I antiarrhythmic medication that was used to treat certain heart rhythm disorders, particularly ventricular arrhythmias. It works by blocking sodium channels in cardiac tissue to stabilize irregular heartbeats. However, the drug has been largely withdrawn from markets due to safety concerns following clinical trials that showed increased mortality risk in certain patient populations.
Moricizine is a discontinued antiarrhythmic medication formerly used for ventricular arrhythmias that was withdrawn due to safety concerns.
Key facts at a glance
- ATC
- C01BG01
- RxNorm
- 40169
- Generic
- Moricizine
- Class
- atc-c01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Moricizine was primarily used for the treatment of ventricular arrhythmias, including ventricular tachycardia and other potentially life-threatening irregular heart rhythms.
As a Class I antiarrhythmic, moricizine blocks sodium channels in cardiac tissue, reducing the rate of impulse conduction and stabilizing the heart's electrical activity to prevent abnormal rhythms.
This medication has been largely discontinued in most countries due to safety concerns. Clinical trials demonstrated an increased risk of mortality in certain patient populations, particularly those with recent myocardial infarction. Due to these risks, its use was largely abandoned in favor of safer alternatives. Cardiac monitoring and close medical supervision are essential if considered.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy