Rifabutin
Mycobutin is an antibiotic medication used primarily to prevent and treat mycobacterial infections, particularly Mycobacterium avium complex (MAC) disease, in patients with compromised immune systems such as those with advanced HIV/AIDS. It belongs to the rifamycin class of antibiotics and works by inhibiting bacterial growth.
Mycobutin is an antibiotic used to prevent and treat MAC and other mycobacterial infections, primarily in immunocompromised patients.
Key facts at a glance
- RxNorm
- 227450
- Generic
- Mycobutin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Mycobutin is indicated for the prevention of Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection. It may also be used in the treatment of established MAC infections and other mycobacterial infections, including tuberculosis and Mycobacterium bovis.
Mycobutin is a rifamycin antibiotic that works by inhibiting bacterial DNA-dependent RNA polymerase, which prevents bacterial RNA synthesis and halts protein production, ultimately stopping bacterial growth.
Common side effects include rash, gastrointestinal upset, and discolored body fluids (urine, tears, sweat). It may cause significant drug interactions with various medications including antiretrovirals, anticoagulants, and hormonal contraceptives. Regular monitoring and periodic ophthalmologic examinations may be recommended during extended treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy