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Naftifine

Published: July 26, 2026Updated: July 26, 2026

Naftifine is a topical antifungal medication used to treat certain fungal skin infections such as athlete's foot (tinea pedis). It is applied directly to the affected skin area to eliminate the fungus causing the infection. This medication is available as a gel and is typically prescribed for adult patients.

Quick summary

Naftifine is a topical antifungal gel used to treat fungal skin infections like athlete's foot.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

ATC
D01AE22
RxNorm
31476
Generic
Naftifine
Class
atc-d01
Brands
Naftin
Availability
rx
Lactation
unknown
Routes
topical
Forms
gel, cream
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Naftifine gel is indicated for the treatment of tinea pedis (athlete's foot) caused by certain fungi. It is for external use only on the skin.

Naftifine is an antifungal agent that works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. This disruption weakens and kills the fungus, clearing the infection.

Naftifine is for topical use only and should not be ingested or applied to mucous membranes, eyes, or internal areas. Patients should follow their healthcare provider's instructions regarding application frequency and duration. Consult a doctor if symptoms do not improve after the prescribed treatment period.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy