Skip to content

Natamycin

Published: July 26, 2026Updated: August 25, 2026

Natamycin is an antifungal medication used to treat fungal infections, particularly those affecting the mouth and digestive tract, by targeting the cell membranes of fungi.

Quick summary

Natamycin is an antifungal medication used to treat fungal infections of the mouth and digestive tract, commonly for conditions like oral thrush.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
A01AB10
RxNorm
7268
Generic
Natamycin
Class
atc-a01
Brands
Natacyn
Availability
rx
Lactation
unknown
Routes
ophthalmic
Forms
suspension
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Natamycin is used to treat fungal infections, particularly oral and gastrointestinal candidiasis (yeast infections). It is commonly prescribed for conditions like oral thrush and may also be used for fungal keratitis (eye infections) and certain skin infections.

Natamycin is a polyene antifungal that works by binding to ergosterol, a key component of fungal cell membranes. This binding creates pores in the membrane, causing the fungal cell contents to leak out and leading to cell death.

Natamycin is typically used for topical or oral administration depending on the infection site. It is generally well-tolerated but may cause local irritation at the application site. Patients should complete the full course of treatment as prescribed and consult their healthcare provider if symptoms persist or worsen.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy