Parathyroid Hormone
Natpara is a parathyroid hormone replacement therapy used to control hypocalcemia (low blood calcium) in adults with chronic hypoparathyroidism. It is prescribed when standard calcium and vitamin D supplementation alone are insufficient to maintain adequate calcium levels. The medication is administered as a daily subcutaneous injection.
Natpara is a parathyroid hormone injection used to treat low calcium levels in adults with chronic hypoparathyroidism.
Key facts at a glance
- RxNorm
- 1602024
- Generic
- Natpara
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Natpara is indicated for the control of hypocalcemia in patients with chronic hypoparathyroidism. It is specifically approved for use in adults who cannot be adequately managed with calcium and vitamin D supplementation alone.
Natpara contains recombinant human parathyroid hormone (1-84), which is identical to the naturally occurring PTH. It works by binding to PTH receptors in bones, kidneys, and other tissues to help regulate calcium and phosphate homeostasis, thereby raising and maintaining blood calcium levels.
Natpara carries a boxed warning due to the potential risk of osteosarcoma observed in animal studies. Regular monitoring of blood calcium levels is required during treatment. The medication should be discontinued if osteosarcoma is suspected. Common side effects may include paresthesia, hypocalcemia, headache, and hypercalcemia.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy