Neisseria Meningitidis Serogroup A CRM197 Conjugate Vaccine
This vaccine provides active immunization against Neisseria meningitidis serogroup A, a bacterium that causes serious infections including meningitis and septicemia. It works by stimulating the immune system to produce protective antibodies against the meningococcal serogroup A polysaccharide capsule.
A conjugate vaccine used to prevent meningococcal disease caused by serogroup A bacteria.
Key facts at a glance
- RxNorm
- 901505
- Generic
- Neisseria Meningitidis Serogroup A Oligosaccharide Diphtheria Crm197 Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Penmenvy, Menveo
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup A. It is recommended for individuals at increased risk of meningococcal exposure or disease, including travelers to endemic regions and those in outbreak situations.
The vaccine contains oligosaccharide antigens from the serogroup A polysaccharide capsule conjugated to CRM197 protein, a nontoxic mutant of diphtheria toxin. This conjugation converts the T-cell independent polysaccharide antigen into a T-cell dependent antigen, enhancing immunogenicity particularly in young children and producing durable immune memory.
Administration is by intramuscular injection. As with all vaccines, this may not protect all recipients, and it does not protect against other meningococcal serogroups. Contraindications include severe hypersensitivity to any vaccine component. Common adverse reactions include injection site reactions, fatigue, and headache.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy