Neisseria Meningitidis Serogroup Y Tetanus Toxoid Conjugate Vaccine
This vaccine provides active immunization against invasive disease caused by Neisseria meningitidis serogroup Y. It is a conjugate vaccine that links capsular polysaccharides to a tetanus toxoid protein carrier to enhance immune response, particularly in younger age groups. The vaccine is primarily used for pre-exposure prophylaxis in adolescents, college students, military personnel, and individuals with certain immunocompromising conditions or who are traveling to or living in endemic areas.
A conjugate vaccine that protects against Neisseria meningitidis serogroup Y, commonly used in adolescents and high-risk populations to prevent meningococcal meningitis and septicemia.
Key facts at a glance
- RxNorm
- 2360574
- Generic
- Neisseria Meningitidis Serogroup Y Capsular Polysaccharide Tetanus Toxoid Protein Conjugate Vaccine
- Class
- unclassified
- Brands
- Menquadfi, Penbraya
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup Y. Commonly recommended for adolescents (typically at age 11-12 with booster at 16), college students living in dormitories, military recruits, and individuals with asplenia or complement deficiencies. May also be used for outbreak control and travelers to hyperendemic regions.
This conjugate vaccine works by stimulating the immune system to produce antibodies against capsular polysaccharides specific to N. meningitidis serogroup Y. The tetanus toxoid protein carrier converts the T-independent polysaccharide antigen into a T-dependent antigen, enabling a stronger and more durable immune response with enhanced immunological memory compared to polysaccharide-only vaccines.
Contraindicated in individuals with known severe allergic reactions to any vaccine component. Common adverse effects include injection site pain, redness, and swelling; systemic reactions such as headache, fatigue, and malaise may occur. Not a substitute for chemoprophylaxis in close contacts of cases. Efficacy depends on inducing protective bactericidal antibodies; duration of protection may require booster doses in some populations.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy