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Chloroprocaine Hydrochloride

Published: July 26, 2026Updated: July 26, 2026

Nesacaine is a brand-name local anesthetic containing chloroprocaine that provides temporary numbness and pain relief during surgical and diagnostic procedures. It is administered by healthcare professionals for nerve blocks, epidural anesthesia, and local infiltration. This medication is typically used when short-acting anesthesia is needed.

Quick summary

Nesacaine is a short-acting local anesthetic used to induce temporary numbness for minor surgical and diagnostic procedures.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
225031
Generic
Nesacaine
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Nesacaine is used for local and regional anesthesia during minor surgical procedures, including infiltration anesthesia, nerve blocks, and epidural anesthesia. It is commonly employed for procedures requiring short to intermediate duration anesthesia.

Nesacaine is an ester-type local anesthetic that works by blocking sodium channels in nerve fibers, preventing the generation and transmission of nerve impulses. This blockade results in temporary loss of sensation and movement in the targeted area.

Nesacaine should only be administered by qualified healthcare professionals. It is contraindicated in patients with known hypersensitivity to ester-type anesthetics or para-aminobenzoic acid (PABA). Adverse effects may include central nervous system stimulation or depression, cardiovascular effects, and allergic reactions. Dosage is individualized based on the procedure, patient condition, and route of administration.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy