Pseudoephedrine Hydrochloride
Nexafed is a brand-name nasal decongestant that contains pseudoephedrine as its active ingredient. It works by narrowing blood vessels in the nasal passages to reduce swelling and congestion. This medication is typically used to temporarily relieve stuffy nose and sinus congestion caused by colds, allergies, or sinus infections.
Nexafed is a pseudoephedrine-based nasal decongestant used to temporarily relieve sinus and nasal congestion.
Key facts at a glance
- RxNorm
- 1361510
- Generic
- Nexafed
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves nasal and sinus congestion from common cold, allergies, hay fever, and sinusitis. May also be used for ear congestion.
Pseudoephedrine is a sympathomimetic (adrenaline-like) agent that causes vasoconstriction of blood vessels in the nasal passages, reducing swelling and congestion.
Should not be used by individuals with certain medical conditions (heart disease, hypertension, thyroid disorders, glaucoma, enlarged prostate). May interact with other medications. Pseudoephedrine products have purchase restrictions in many countries due to potential for abuse in manufacturing illicit substances. Consult a healthcare provider before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy