Sorafenib
Nexavar (sorafenib) is a prescription cancer medication classified as a multikinase inhibitor. It is primarily used to treat certain types of kidney cancer (renal cell carcinoma), liver cancer (hepatocellular carcinoma), and thyroid cancer that has spread to other parts of the body.
Nexavar is a targeted cancer therapy used to treat advanced kidney, liver, and thyroid cancers by inhibiting multiple enzymes involved in tumor growth and blood vessel formation.
Key facts at a glance
- RxNorm
- 619985
- Generic
- Nexavar
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Nexavar is indicated for the treatment of advanced renal cell carcinoma (kidney cancer), unresectable hepatocellular carcinoma (liver cancer), and locally recurrent or metastatic, progressive, differentiated thyroid carcinoma refractory to radioactive iodine treatment.
Nexavar works as a multikinase inhibitor by blocking enzymes (kinases) that promote abnormal cell growth and the formation of new blood vessels that feed tumors. It inhibits pathways involved in both tumor proliferation and angiogenesis.
Nexavar is a prescription-only medication that may cause serious side effects including hand-foot skin reaction, hypertension, cardiac events, bleeding problems, and wound healing complications. Regular monitoring by a healthcare provider is required during treatment. Patients should inform their doctor of all medications and health conditions before starting therapy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy