Bromelain
Nexobrid is a topical proteolytic enzyme medication derived from bromelain, an extract from pineapple stems. It is applied to burn wounds as a gel to enzymatically break down and remove dead tissue (eschar), preparing the wound bed for further treatment. This medication is specifically used in adult patients with deep partial-thickness and/or full-thickness thermal burns.
Nexobrid is a topical enzyme treatment that removes dead burn tissue to help prepare wounds for healing and skin grafting.
Key facts at a glance
- RxNorm
- 2626743
- Generic
- Nexobrid
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Nexobrid is used for eschar removal (debridement) in adults with deep partial-thickness and/or full-thickness thermal burns. It helps prepare burn wounds for subsequent treatment, including skin grafting.
Nexobrid contains a concentrate of proteolytic enzymes that break down proteins in dead tissue (eschar). When applied topically to burn wounds, these enzymes selectively digest necrotic tissue while largely sparing healthy tissue, allowing for more efficient and targeted debridement.
Nexobrid should only be administered by healthcare professionals trained in its use. It is contraindicated for application on the face, perineum, or genitalia. Potential side effects include local skin reactions, pain during treatment, and hypersensitivity reactions. Treatment typically requires a single 4-hour application followed by thorough wound cleansing.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy