Nizatidine
Nizatidine is an H2 receptor antagonist that treats excess stomach acid, ulcers, and GERD by reducing acid production.
Nizatidine is an acid-reducing medication that treats ulcers and GERD by blocking histamine H2 receptors in the stomach.
Key facts at a glance
- ATC
- A02BA04
- RxNorm
- 42319
- Generic
- Nizatidine
- Class
- atc-a02
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution, capsule, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Nizatidine treats and prevents stomach (gastric) and intestinal (duodenal) ulcers, manages gastroesophageal reflux disease (GERD), and addresses conditions involving excessive stomach acid production. It may also be used for Zollinger-Ellison syndrome.
As an H2 receptor antagonist, Nizatidine blocks histamine H2 receptors on stomach parietal cells, preventing acid secretion. This reduces stomach acid output, creating a less acidic environment that allows ulcers to heal and alleviates acid-related symptoms.
Nizatidine has been withdrawn from the US market due to concerns about NDMA contamination. It should not be used in patients with known hypersensitivity to H2 blockers. Dose adjustment may be needed in patients with kidney impairment. Common side effects may include headache, dizziness, and diarrhea.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy