Desmopressin Acetate
Noctiva is a brand-name nasal spray medication containing desmopressin, used to treat nocturnal polyuria (excessive nighttime urination) in adults. It works by mimicking vasopressin, an antidiuretic hormone that helps reduce urine production during the night, allowing patients to sleep without frequent bathroom trips.
Noctiva is a nasal spray medication for adults with nocturnal polyuria that reduces nighttime urination by mimicking an antidiuretic hormone.
Key facts at a glance
- RxNorm
- 1874125
- Generic
- Noctiva
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Noctiva is used to treat nocturnal polyuria in adults, a condition characterized by excessive nighttime urination that disrupts sleep quality and daily functioning.
Noctiva contains desmopressin, a synthetic analog of the natural hormone vasopressin. It acts on V2 receptors in the kidneys' collecting ducts to increase water reabsorption, thereby decreasing urine production during nighttime hours.
Noctiva is administered as a nasal spray. It should not be used in patients with certain conditions including severe kidney impairment, hyponatremia, or SIADH. Patients should follow dosage instructions carefully and be aware of fluid intake restrictions to minimize risks of water retention and low sodium levels.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy