Hydrocodone Bitartrate and Acetaminophen
Norco is a prescription combination medication containing hydrocodone (an opioid) and acetaminophen (a non-opioid pain reliever). It is used to manage moderate to severe pain when other treatments are not sufficient. This medication requires a prescription and is typically reserved for situations where pain is severe enough to require an opioid.
Norco is an opioid-based pain medication combining hydrocodone and acetaminophen, prescribed for moderate to severe pain relief.
Key facts at a glance
- RxNorm
- 218772
- Generic
- Norco
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Norco is prescribed for the relief of moderate to moderately severe pain. It is typically used when other non-opioid pain medications have not provided adequate relief. Common uses include post-operative pain, injury-related pain, and other conditions requiring strong pain management.
Norco contains two active ingredients that work together to relieve pain. Hydrocodone binds to opioid receptors in the brain and nervous system to reduce the perception of pain and produce calming effects. Acetaminophen enhances the pain-relieving effects and may also work by affecting certain brain chemicals involved in pain signaling.
Norco is a Schedule II controlled substance due to its opioid component and carries a risk of dependence, addiction, and misuse. The acetaminophen component can cause serious liver damage if taken in excessive amounts. Patients should not consume alcohol while taking Norco and should inform their doctor of all medications they are taking to avoid dangerous interactions. Common side effects include drowsiness, dizziness, constipation, and nausea. This medication should only be used exactly as prescribed by a healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy