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Norfloxacin

Published: July 26, 2026Updated: August 25, 2026

Norfloxacin is a fluoroquinolone antibiotic used to treat various bacterial infections, particularly those affecting the urinary tract and gastrointestinal system. It works by inhibiting bacterial enzymes essential for DNA replication and transcription, effectively stopping the growth and spread of susceptible bacteria.

Quick summary

Norfloxacin is a fluoroquinolone antibiotic primarily prescribed for urinary tract and gastrointestinal bacterial infections.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
J01MA06
RxNorm
7517
Generic
Norfloxacin
Class
atc-j01
Brands
—
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Norfloxacin is primarily used to treat uncomplicated urinary tract infections (cystitis), complicated urinary tract infections, and gonorrhea. It may also be prescribed for bacterial gastroenteritis, prostatitis, and certain sexually transmitted infections when caused by susceptible organisms.

Norfloxacin belongs to the fluoroquinolone class of antibiotics. It works by inhibiting two key bacterial enzymes—DNA gyrase and topoisomerase IV—which are essential for bacterial DNA replication, transcription, and repair. By disrupting these processes, the medication prevents bacteria from multiplying and spreading.

Common side effects may include nausea, headache, and dizziness. Fluoroquinolones carry FDA black box warnings for serious adverse effects including tendinitis, tendon rupture, and peripheral neuropathy. This medication may increase sensitivity to sunlight and can interact with antacids, caffeine, and blood thinners. Patients with a history of seizures or myasthenia gravis should use this medication with caution.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy