Omadacycline
Nuzyra (omadacycline) is a broad-spectrum tetracycline antibiotic used to treat serious bacterial infections. It is FDA-approved for community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI). The medication is available in both intravenous and oral formulations, allowing for flexible dosing strategies.
Nuzyra is a tetracycline-class antibiotic used to treat pneumonia and skin infections in adults.
Key facts at a glance
- RxNorm
- 2059275
- Generic
- Nuzyra
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Nuzyra is indicated for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in adult patients.
As a tetracycline-class antibiotic, omadacycline works by binding to the bacterial 30S ribosomal subunit and blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor (A) site, thereby inhibiting bacterial protein synthesis.
Nuzyra is contraindicated in patients with known hypersensitivity to tetracyclines. Common side effects include nausea, vomiting, and infusion site reactions. Like other tetracyclines, it may cause photosensitivity and is not recommended for use during tooth development in children.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy