Ofloxacin
Ofloxacin is a fluoroquinolone antibiotic used to treat a variety of bacterial infections including respiratory tract infections, urinary tract infections, skin infections, and certain sexually transmitted infections. It works by inhibiting bacterial DNA synthesis, effectively stopping the growth and replication of susceptible bacteria.
Ofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat various bacterial infections by inhibiting bacterial DNA replication.
Key facts at a glance
- ATC
- J01MA01
- RxNorm
- 7623
- Generic
- Ofloxacin
- Class
- atc-j01
- Brands
- Ocuflox
- Availability
- rx
- Lactation
- unknown
- Routes
- oral, otic, ophthalmic
- Forms
- tablet, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ofloxacin treats respiratory infections (such as pneumonia and bronchitis), urinary tract infections, skin and soft tissue infections, prostatitis, and sexually transmitted infections including gonorrhea and chlamydia. It is effective against both gram-positive and gram-negative bacteria.
Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. By blocking these enzymes, it prevents bacteria from multiplying and spreading.
Common side effects include nausea, diarrhea, headache, and dizziness. Patients should avoid excessive sunlight exposure as photosensitivity reactions may occur. Fluoroquinolones may increase the risk of tendinitis and tendon rupture, particularly in older adults and those taking corticosteroids. Ofloxacin may also cause central nervous system effects including seizures and confusion.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy