Ogivri
Ogivri is a biosimilar medication referencing Herceptin, belonging to the HER2/neu receptor antagonist class. It is primarily used to treat certain HER2-positive cancers, including breast cancer and gastric cancer.
Ogivri is a brand-name biosimilar used to treat HER2-positive breast and gastric cancers.
Key facts at a glance
- RxNorm
- 2179754
- Generic
- Ogivri
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ogivri is indicated for the treatment of HER2-positive breast cancer (early-stage, metastatic, and as adjuvant therapy) and HER2-positive gastric or gastroesophageal junction adenocarcinoma. It is typically used when tumors overexpress the HER2 protein.
As a biosimilar to trastuzumab, Ogivri is a monoclonal antibody that targets the HER2 protein on cancer cells, inhibiting tumor cell proliferation and potentially mediating antibody-dependent cellular cytotoxicity (ADCC).
Ogivri carries warnings for potential cardiotoxicity (heart problems), including decreased left ventricular ejection fraction, and requires cardiac monitoring during treatment. It may cause serious infusion reactions. This is a specialty medication typically administered intravenously by healthcare professionals. Patients should inform their doctor of any heart conditions, pregnancy status, or breathing problems before treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy