Phenylephrine and Ketorolac
Omidria is a sterile intraocular solution combining phenylephrine and ketorolac, used during cataract surgery and other intraocular lens replacement procedures. It maintains pupil dilation throughout the surgical procedure while reducing inflammation and pain. This prescription medication is specifically indicated for adult patients undergoing ocular surgery.
Omidria is an intraoperative ophthalmic solution that maintains pupil dilation and reduces surgical inflammation during cataract procedures.
Key facts at a glance
- RxNorm
- 1540231
- Generic
- Omidria
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Omidria is indicated for maintaining mydriasis (pupil dilation) during cataract surgery and intraocular lens replacement, as well as reducing postoperative ocular pain and inflammation associated with these procedures in adults.
Omidria combines two active ingredients: phenylephrine, an alpha-adrenergic agonist that stimulates pupil dilation, and ketorolac, a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting prostaglandin synthesis. The solution is instilled directly into the anterior chamber during surgery.
Omidria is for intraoperative use only and should not be administered preoperatively or postoperatively. It is contraindicated in patients with hypersensitivity to any components or other NSAIDs. Common adverse reactions may include anterior chamber inflammation, increased intraocular pressure, and ocular discomfort. Healthcare providers should monitor patients appropriately during and after surgical procedures.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy