Omvoh
Omvoh (mirikizumab) is a prescription biologic medication used to treat adults with moderate to severe ulcerative colitis and Crohn's disease. It is an injectable monoclonal antibody that targets interleukin-23 (IL-23), a key protein involved in inflammatory responses. By blocking IL-23, Omvoh helps reduce inflammation in the gastrointestinal tract and improve symptoms such as abdominal pain, diarrhea, and rectal bleeding.
Omvoh is a biologic drug used to treat inflammatory bowel diseases like ulcerative colitis and Crohn's disease by blocking the IL-23 inflammatory pathway.
Key facts at a glance
- RxNorm
- 2668393
- Generic
- Omvoh
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Omvoh is FDA-approved for the treatment of moderate to severe ulcerative colitis in adults and Crohn's disease in adults. It is typically used when other treatments have not been effective or are not tolerated.
Omvoh is a monoclonal antibody that specifically binds to and neutralizes interleukin-23 (IL-23), a cytokine that plays a central role in chronic inflammation. By inhibiting IL-23, it reduces the inflammatory response in the gut lining, helping to control symptoms and promote remission.
Omvoh is administered by subcutaneous injection, typically after initial intravenous loading doses. Common side effects may include upper respiratory infections, headache, and injection site reactions. As a biologic, it may increase the risk of infections and should not be used with live vaccines. Patients should be screened for tuberculosis before starting treatment. Regular monitoring by a healthcare provider is essential.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy