Oritavancin
Orbactiv (oritavancin) is a lipoglycopeptide antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria. It is administered as a single intravenous dose, which can be advantageous for patients who may have difficulty completing multi-day antibiotic regimens. This medication is designed for adults and works by targeting the bacterial cell wall.
Orbactiv is an IV antibiotic for skin infections that works with just a single dose.
Key facts at a glance
- RxNorm
- 1547616
- Generic
- Orbactiv
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Orbactiv is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is approved for use in adult patients.
Orbactiv is a lipoglycopeptide antibiotic that works through multiple mechanisms, including inhibition of bacterial cell wall synthesis and disruption of bacterial cell membrane integrity, leading to bacterial death.
Orbactiv is administered as a single 3-hour intravenous infusion. It should not be given to patients with known hypersensitivity to the drug. Common side effects may include headache, nausea, and infusion-related reactions. Blood tests measuring coagulation parameters may be affected for up to 48 hours after dosing.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy