Oritavancin
Oritavancin is a lipoglycopeptide antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria. It is administered intravenously and works by inhibiting bacterial cell wall synthesis. Due to its long half-life, oritavancin may be given as a single-dose regimen, which can be beneficial for outpatient treatment and improving patient compliance.
An IV lipoglycopeptide antibiotic for treating skin infections caused by gram-positive bacteria, often given as a single dose.
Key facts at a glance
- ATC
- J01XA05
- RxNorm
- 1547611
- Generic
- Oritavancin
- Class
- atc-j01
- Brands
- Orbactiv, Kimyrsa
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive organisms, including methicillin-resistant Staphylococcus aureus (MRSA).
Oritavancin is a lipoglycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to the D-Ala-D-Ala terminus of peptidoglycan precursors, disrupting bacterial growth.
Administered intravenously. Has a long terminal half-life allowing for single-dose treatment. May interact with anticoagulant drugs and can affect certain laboratory tests. Contraindicated in patients with hypersensitivity to the drug. Not recommended for use in pediatric patients.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy