Mannitol
Osmitrol (mannitol) is an osmotic diuretic medication used to reduce swelling and pressure in the brain and eyes, and to promote urine production in certain kidney conditions. It works by drawing fluid from body tissues into the bloodstream, which is then filtered and excreted by the kidneys.
Osmitrol is a brand-name diuretic used to reduce brain and eye pressure, and to promote kidney function in specific conditions.
Key facts at a glance
- RxNorm
- 202697
- Generic
- Osmitrol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of elevated intracranial or intraocular pressure, prevention of acute kidney failure, and enhancement of renal excretion of certain toxic substances.
Osmitrol is an osmotic diuretic that creates a hypertonic solution in the bloodstream, drawing excess fluid from tissues (particularly brain and eye tissue) into circulation, which is then eliminated through the kidneys.
Administered by intravenous infusion. Requires careful monitoring of fluid balance, electrolytes, and renal function. Contraindicated in anuria, severe dehydration, and active intracranial bleeding. May cause electrolyte imbalances, particularly hyponatremia.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy