Voxelotor
Oxbryta (voxelotor) is a prescription medication used to treat sickle cell disease in adults and children 4 years of age and older. It works by binding to hemoglobin and increasing its affinity for oxygen, which helps prevent red blood cells from sickling and breaking apart. This can reduce complications associated with sickle cell disease.
Oxbryta is a hemoglobin S polymerization inhibitor used to treat sickle cell disease by preventing red blood cells from sickling.
Key facts at a glance
- RxNorm
- 2265684
- Generic
- Oxbryta
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Oxbryta is indicated for the treatment of sickle cell disease to reduce hemolytic anemia and improve oxygen delivery to tissues. It is approved for use in both adults and pediatric patients aged 4 years and older.
Oxbryta is a hemoglobin S (HbS) polymerization inhibitor. It binds directly to HbS and stabilizes the oxygenated hemoglobin state, preventing the deoxygenation-induced polymerization that causes red blood cells to sickle. This action reduces hemolysis and improves red blood cell survival.
Common side effects may include headache, diarrhea, abdominal pain, and fatigue. Patients should be monitored for hypersensitivity reactions. The medication is taken orally once daily, with or without food. Patients should continue to follow their healthcare provider's guidance regarding disease management and any other treatments.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy