Oxyquinoline
Oxyquinoline is a topical antiseptic agent used in dental and oral care preparations, known for its antibacterial and antifungal properties that help reduce microbial growth in the oral cavity.
Oxyquinoline is an antiseptic medication used in oral/dental preparations to reduce bacteria and fungi in the mouth.
Key facts at a glance
- ATC
- A01AB07
- RxNorm
- 110
- Generic
- Oxyquinoline
- Class
- atc-a01
- Brands
- Fem pH, Relagard, Trimo San
- Availability
- rx
- Lactation
- unknown
- Routes
- vaginal, topical
- Forms
- gel, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
11 groupspregnancy
first trimesteruse only if clearly needed
avoid use during pregnancy unless benefits outweigh risks - limited systemic absorption but caution advised
regular prenatal check-ups
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse only if clearly needed
topical vaginal use acceptable with medical supervision
routine prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse only if clearly needed
can be used for vaginal preparations under medical supervision
routine prenatal monitoring
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse with caution
limited data on breast milk transfer - topical application preferred
monitor infant for any adverse effects
Use with caution and monitor for adverse effects.
pediatric_age
infantsnot recommended
avoid use in infants and young children
not applicable
Use of this medication in this population requires careful consideration of risks and benefits.
pediatric_age
children 2 12use with extreme caution
use only under medical supervision in children over 2 years
close medical supervision required
Use with caution and monitor for adverse effects.
geriatric
elderlyno adjustment typically required
standard dosing appropriate for elderly patients
standard monitoring
renal_impairment
mildno adjustment required
standard dosing - minimal systemic absorption
standard monitoring
renal_impairment
severeuse with caution
use only if benefits outweigh risks
monitor renal function periodically
Use with caution and monitor for adverse effects.
hepatic_impairment
mild to moderateno adjustment required
standard dosing - minimal hepatic metabolism
standard monitoring
hepatic_impairment
severeuse with caution
use only under medical supervision
monitor liver function
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information for vaginal antiseptic preparations
Drug class
Drug class information for Oxyquinoline
Common uses
Common therapeutic uses in Fem pH, Relagard, Trimo San
Common formulations
Available pharmaceutical forms
Used for oral hygiene maintenance, gingivitis, minor mouth infections, and as a component in antiseptic mouthwashes. Also used topically for minor skin infections in some formulations.
Exerts antiseptic effects by disrupting microbial cell membranes and inhibiting enzyme systems in bacteria and fungi. Acts locally without significant systemic absorption when applied topically.
For topical/oral use only. Avoid ingestion of large amounts. May cause local irritation in some users. Consult a healthcare provider if symptoms persist beyond 7 days. Not recommended for use in children under 12 without medical advice.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy