Ozenoxacin
Ozenoxacin is a topical antibiotic medication used to treat impetigo, a common bacterial skin infection characterized by red sores and honey-colored crusts. It is applied directly to the affected skin areas and is approved for use in both adults and children as young as 2 months old.
A topical antibiotic cream used to treat impetigo and other superficial skin infections.
Key facts at a glance
- ATC
- D06AX14
- RxNorm
- 1994739
- Generic
- Ozenoxacin
- Class
- atc-d06
- Brands
- Xepi
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- cream
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of impetigo (including impetigo contagiosa) and impetiginized dermatitis caused by susceptible bacteria such as Staphylococcus aureus and Streptococcus pyogenes. Commonly presents as red sores or honey-colored crusts on the face and body.
Ozenoxacin is a non-fluorinated quinolone antibiotic that works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication, thereby stopping the growth and spread of susceptible bacteria.
For topical use only; avoid contact with eyes, nose, and mouth. Should be applied as a thin layer to the affected area(s) twice daily. Not recommended for use on large areas of broken skin or for extended durations. Safety and effectiveness in children under 2 months of age have not been established. May cause local skin reactions such as irritation or redness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy