Pancrelipase
Pancreaze is a brand-name prescription medication containing pancreatic enzymes (lipase, protease, and amylase) used to replace missing digestive enzymes in people with exocrine pancreatic insufficiency. It is commonly prescribed for patients with cystic fibrosis, chronic pancreatitis, pancreatic cancer, or those who have had pancreatic surgery. The medication helps the body break down and absorb fats, proteins, and carbohydrates from food.
Pancreaze provides digestive enzymes to help people with pancreatic insufficiency absorb nutrients from food.
Key facts at a glance
- RxNorm
- 1372686
- Generic
- Pancreaze
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Pancreaze is used to treat exocrine pancreatic insufficiency (EPI), a condition where the pancreas cannot produce enough digestive enzymes. It is prescribed for patients with cystic fibrosis, chronic pancreatitis, pancreatic cancer, pancreatic surgery, or other conditions that impair pancreatic function.
Pancreaze contains a combination of digestive enzymes that work in the small intestine to break down fats (via lipase), proteins (via protease), and carbohydrates (via amylase) from food, allowing for proper nutrient absorption.
Pancreaze should be taken with meals and/or snacks as directed by a healthcare provider. Capsules may be swallowed whole or opened and sprinkled on soft food. Dosing is individualized based on diet, symptom severity, and fecal fat testing. Patients should avoid crushing or chewing capsules. Common side effects may include abdominal discomfort, nausea, or changes in bowel movements. Close monitoring is recommended, particularly in cystic fibrosis patients.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy