Pancreatin
Pancreplus is a brand-name pancreatic enzyme replacement therapy containing digestive enzymes (lipase, protease, and amylase) that help break down fats, proteins, and carbohydrates in the digestive tract. It is prescribed for patients with pancreatic insufficiency, including those with cystic fibrosis, chronic pancreatitis, or who have undergone pancreatic surgery, to aid in proper food digestion and nutrient absorption.
Brand-name pancreatic enzyme supplement used to replace missing digestive enzymes in patients with pancreatic insufficiency.
Key facts at a glance
- RxNorm
- 1423484
- Generic
- Pancreplus
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of exocrine pancreatic insufficiency associated with cystic fibrosis, chronic pancreatitis, pancreatic surgery, pancreatic cancer, and other conditions where the pancreas cannot produce adequate digestive enzymes.
Contains pancrelipase derived from porcine pancreas, providing lipase (for fat digestion), protease (for protein digestion), and amylase (for carbohydrate digestion) to compensate for deficient natural enzyme production and support normal nutrient absorption.
Must be taken with meals and/or snacks as directed; capsules or contents should not be crushed or chewed (micro-spheres can be mixed with soft food). Dosage is individualized based on weight, diet, and symptom severity. May cause GI side effects such as nausea, abdominal pain, or constipation. Patients should maintain adequate fluid intake. Effectiveness depends on proper timing with food intake.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy