Peginterferon Alfa-2b
Peginterferon Alfa-2b is a pegylated form of interferon alfa-2b, an immunomodulatory and antiviral protein. It is used to treat certain chronic viral infections and cancers by enhancing the body's immune response against infected and malignant cells.
Peginterferon Alfa-2b is an injectable immunomodulatory drug used to treat chronic hepatitis B, hepatitis C, and certain cancers by boosting immune function and inhibiting viral replication.
Key facts at a glance
- ATC
- L03AB10
- RxNorm
- 253453
- Generic
- Peginterferon Alfa-2b
- Class
- atc-l03
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Chronic Hepatitis B infection, Chronic Hepatitis C infection (often in combination with other antiviral agents), and adjuvant treatment of malignant melanoma in certain patients.
Peginterferon Alfa-2b binds to interferon receptors on cell surfaces, activating intracellular signaling pathways that result in antiviral, antiproliferative, and immunomodulatory effects, helping the immune system combat viral infections and cancer cells.
Administered by subcutaneous injection, typically once weekly. Requires regular monitoring of blood counts, liver function, and thyroid function. Common side effects include flu-like symptoms, depression, and fatigue. Contraindicated in pregnancy and in patients with certain autoimmune or psychiatric conditions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy