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Famotidine, Calcium Carbonate, Magnesium Hydroxide

Published: July 26, 2026Updated: July 26, 2026

Pepcid Complete is an over-the-counter medication that combines an H2 blocker (famotidine) with antacids (calcium carbonate and magnesium hydroxide) to provide relief from heartburn, acid indigestion, and sour stomach. It works by both neutralizing existing stomach acid and reducing the production of additional acid, offering both quick and lasting relief.

Quick summary

Pepcid Complete is a combination antacid and acid reducer used to treat heartburn and indigestion by neutralizing and decreasing stomach acid production.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
284831
Generic
Pepcid Complete
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Pepcid Complete is used to treat and prevent symptoms of heartburn, acid indigestion, sour stomach, and gastroesophageal reflux (GERD). It provides relief from symptoms caused by overeating, drinking certain foods/beverages, or stomach acid.backing up into the esophagus.

The medication contains two active ingredients that work together: famotidine blocks histamine H2 receptors in the stomach, reducing acid production for up to 12 hours, while calcium carbonate and magnesium hydroxide provide rapid neutralization of existing stomach acid for quick symptom relief.

This is an OTC product intended for short-term use (typically 2 weeks or less for self-treatment). Patients should consult a healthcare provider if symptoms persist, worsen, or occur frequently. Those with kidney disease, ulcers, or who are pregnant should seek medical advice before use. Avoid taking with certain medications without consulting a doctor, as antacids can affect absorption of other drugs.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy