Bismuth Subsalicylate
Pepto-Bismol is an over-the-counter brand-name medication containing bismuth subsalicylate, used to treat diarrhea, heartburn, indigestion, nausea, and upset stomach. It works by coating the stomach lining, reducing inflammation, and inhibiting bacterial growth in the digestive tract. This medication is commonly used by adults and children over 12 years old for short-term relief of gastrointestinal symptoms.
Pepto-Bismol is an OTC stomach relief medication used to treat diarrhea, heartburn, and indigestion by coating the stomach lining and reducing inflammation.
Key facts at a glance
- RxNorm
- 54536
- Generic
- Pepto-Bismol
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Pepto-Bismol treats acute diarrhea, traveler's diarrhea, heartburn, acid indigestion, sour stomach, nausea, and gas. It is FDA-approved for adults and children 12 years and older.
Bismuth subsalicylate works through multiple mechanisms: it coats the stomach and intestinal lining to protect irritated tissue, has mild antimicrobial properties against certain bacteria, reduces inflammation in the digestive tract, and may help absorb excess fluids and electrolytes in the intestines.
Contains a salicylate component related to aspirin; avoid if allergic to salicylates or if taking blood thinners. Should not be used in children or teenagers recovering from viral infections due to Reye's syndrome risk. May cause temporary darkening of tongue or stool. Consult a doctor before use during pregnancy or if symptoms persist beyond 2 days. Not intended for long-term use without medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy