Skip to content

Chlorhexidine Gluconate

Published: July 26, 2026Updated: July 26, 2026

Peridex is a prescription antiseptic oral rinse containing chlorhexidine gluconate, primarily used to treat gingivitis and reduce gum inflammation. It is commonly prescribed by dentists to help control plaque buildup and promote healing after dental procedures. This medication is intended for short-term use as part of a comprehensive oral hygiene regimen.

Quick summary

Peridex is a prescription antiseptic mouthwash used to treat gingivitis and reduce oral bacteria, commonly prescribed after dental procedures.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
224891
Generic
Peridex
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Peridex is indicated for the treatment of gingivitis, characterized by redness, swelling, and bleeding of the gums. It is also used to reduce oral bacteria following dental surgery or procedures, and to help control plaque accumulation in patients with oral health conditions.

Chlorhexidine gluconate, the active ingredient in Peridex, is an antimicrobial agent that binds to oral tissues and provides sustained antibacterial activity. It works by disrupting bacterial cell membranes, reducing the overall bacterial load in the mouth and helping to prevent plaque formation.

Peridex is for oral use only and should not be swallowed. Common side effects may include temporary staining of teeth, altered taste sensation, and increased tartar buildup. Use is typically limited to short-term treatment (2 weeks to 6 months) as directed by a healthcare provider. Patients should avoid eating, drinking, or rinsing immediately after using this medication to allow it to work effectively.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy