Doxycycline
Periostat is a brand-name formulation of doxycycline specifically indicated for the treatment of periodontitis (gum disease). It contains sub-antimicrobial doses of the tetracycline antibiotic and works primarily through anti-inflammatory mechanisms rather than traditional antibiotic action. This medication was developed as an adjunct to scaling and root planing procedures for patients with periodontal disease.
Periostat is a low-dose doxycycline medication used to treat gum disease by reducing inflammation.
Key facts at a glance
- RxNorm
- 219170
- Generic
- Periostat
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of adult periodontitis as an adjunct to scaling and root planing. It is specifically formulated for patients with gum disease to help reduce pocket depth and manage bacterial inflammation in the gums.
The exact mechanism is not fully specified, but it is believed to work through anti-inflammatory properties at sub-antimicrobial doses rather than through direct antibiotic action against bacteria.
Periostat is a brand-name formulation that may no longer be available, though generic alternatives may exist. As with all tetracycline antibiotics, it may cause photosensitivity and should not be used during pregnancy or in children under 8 years of age. Patients should consult their healthcare provider for current availability and appropriate alternatives.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy