Pertuzumab
Perjeta (pertuzumab) is a prescription monoclonal antibody used to treat HER2-positive breast cancer. It is administered intravenously, typically in combination with other cancer medications. This targeted therapy is used for both metastatic and early-stage HER2-positive breast cancer.
Perjeta is a targeted HER2-positive breast cancer treatment given by IV infusion, usually with other cancer medications.
Key facts at a glance
- RxNorm
- 1298949
- Generic
- Perjeta
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Perjeta is used to treat HER2-positive breast cancer that has spread to other parts of the body (metastatic) or that is in the early stages with a high risk of returning. It is specifically for patients whose tumors have the HER2 protein on their cancer cells.
Perjeta is a monoclonal antibody that targets the HER2 protein on cancer cells. It binds to the HER2 receptor and prevents it from pairing with other HER receptors, which blocks signals that tell cancer cells to grow and divide. This slows cancer progression.
Perjeta can cause heart problems, including decreased heart function. Infusion reactions may occur during or after treatment. It is typically given with trastuzumab and chemotherapy. Tell your doctor if you are pregnant, planning pregnancy, or have heart problems. Regular heart monitoring is required during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy