Pancrelipase
Pertzye is a brand-name pancreatic enzyme replacement therapy (PERT) used to aid digestion in individuals whose pancreas cannot produce sufficient digestive enzymes. It is primarily prescribed for patients with cystic fibrosis, chronic pancreatitis, or those who have had their pancreas surgically removed. The medication helps break down fats, proteins, and carbohydrates to prevent malabsorption and associated nutritional deficiencies.
Pertzye is a pancreatic enzyme supplement used to treat digestive insufficiency caused by conditions like cystic fibrosis or chronic pancreatitis, helping patients absorb nutrients from food.
Key facts at a glance
- RxNorm
- 1294123
- Generic
- Pertzye
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Pertzye is indicated for the treatment of exocrine pancreatic insufficiency (EPI) caused by cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions that result in inadequate pancreatic enzyme production. It helps manage symptoms such as fatty stools (steatorrhea), weight loss, and nutritional deficiencies.
Pertzye contains a combination of digestive enzymes (lipase, protease, and amylase) that replace the enzymes normally produced by the pancreas. These enzymes work in the small intestine to break down fats, proteins, and carbohydrates into absorbable forms, allowing the body to properly digest and utilize nutrients from food.
Pertzye should be taken with meals or snacks, and the capsules may be opened and mixed with soft food for those who have difficulty swallowing. Dosing is typically based on the fat content of the meal. Patients should not crush or chew the beads inside the capsules. Always follow prescribing healthcare provider instructions and inform your doctor of any unusual abdominal symptoms or allergic reactions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy