Promethazine
Phenadoz is a brand-name antihistamine medication containing promethazine. It is primarily used to treat allergic conditions, nausea, vomiting, motion sickness, and to produce sedation before or after surgical procedures. This medication belongs to the phenothiazine class of antihistamines and works by blocking histamine receptors in the body.
Phenadoz is an antihistamine used for allergies, nausea, and sedation.
Key facts at a glance
- RxNorm
- 541158
- Generic
- Phenadoz
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Phenadoz is used to treat allergic reactions, allergic rhinitis, allergic skin conditions, nausea and vomiting (including post-operative and motion-induced), and as a pre-operative sedative. It may also be used for the symptomatic relief of upper respiratory allergies.
Phenadoz contains promethazine, a first-generation antihistamine that blocks H1 histamine receptors. It also has antiemetic properties and demonstrates sedative effects through central nervous system depression.
Phenadoz may cause drowsiness and should not be used in children under 2 years old due to the risk of respiratory depression. It can interact with other CNS depressants, including alcohol. Use with caution in patients with respiratory conditions, glaucoma, or urinary retention. This is a prescription medication that should only be used under medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy